Eddie Murphy

Dr. John Dolittle

Acting

Ossie Davis

Archer Dolittle

Acting

Oliver Platt

Dr. Mark Weller

Acting

Peter Boyle

Calloway

Acting

Richard Schiff

Dr. Gene Reiss

Acting

Kristen Wilson

Lisa

Acting

Jeffrey Tambor

Dr. Fish

Acting

Kyla Pratt

Maya

Acting

Raven-Symoné

Charisse

Acting

Steven Gilborn

Dr. Litvack

Acting

Erik Dellums

Jeremy

Acting

June Christopher

Diane

Acting

Cherie Franklin

Mrs. Parkus

Acting

Norm Macdonald

Lucky (voice)

Acting

Chris Rock

Rodney (voice)

Acting

Albert Brooks

Tiger (voice)

Acting

Jenna Elfman

Owl (Voice)

Acting

Reni Santoni

Rat #1 (Voice)

Acting

John Leguizamo

Rat #2 (Voice)

Acting

Julie Kavner

Female Pigeon (voice)

Acting

Garry Shandling

Male Pigeon (voice)

Acting

Ellen DeGeneres

Prologue Dog (voice)

Acting

Paul Reubens

Raccoon (voice)

Acting

Eddie Frierson

Skunk (voice)

Acting

Phil Proctor

Drunk Monkey (Voice)

Acting

Gilbert Gottfried

Compulsive Dog (Voice)

Acting

Brian Doyle-Murray

Old Beagle (voice)

Acting

Douglas Shamburger

Pound Dog (voice)

Sound

Jeff Doucette

Possum (voice)

Acting

Archie Hahn

Heavy Woman's Dog (voice)

Acting

Tom Towles

German Shepherd (voice)

Acting

Royce D. Applegate

'I Love You' Dog (voice)

Acting

Chad Einbinder

Bettleheim the Cat (voice)

Acting

Jonathan Lipnicki

Baby Tiger (voice)

Acting

Hamilton Camp

Pig (voice)

Acting

Kerrigan Mahan

Penguin (voice)

Acting

Mark Adair-Rios

Intern

Acting

Don Calfa

Patient at Hammersmith

Acting

Kellye Nakahara

Beagle Woman

Acting

Beth Grant

Woman

Acting

Yule Caise

Vet's Assistant

Acting

Charles Branklyn

Security Guard

Acting

Richard Penn

Mr. Galvin

Acting

Karl T. Wright

Reporter

Acting

Stan Sellers

Cop #1

Acting

Ming Lo

Cop #2

Acting

Paul Giamatti

Blaine (uncredited)

Acting

Benny Buettner

Circus Clown (uncredited)

Acting

Pruitt Taylor Vince

Patient at Hammersmith (uncredited)

Acting

Crystal the Monkey

Drunk Monkey (uncredited)

Acting

Kellan Patrick

Jumping Boy (uncredited)

Acting

Kay Yamamoto

Receptionist

Acting

Brian Kwan

Busboy

Production

L. Peter Callender

Policeman

Acting

Arnold F. Turner

Animal Control Officer

Acting

Raymond Matthew Mason

3-Year-Old John Dolittle

Acting

John Lafayette

Reverend

Acting

Phyllis Katz

Goat (voice)

Acting

Dari Gerard Smith

5-Year-Old John Dolittle

Acting

Bebe Conrad

Circus Clown (uncredited)

Acting

Cliff McLaughlin

Mounted Policeman

Crew

James F. Dean

Orangutan (voice)

Acting